News from InspectT: UV/Vis optical DOSY

Uv/Vis-DOSY plot measured for a mixture containing caffeine and CGA.

We are proud to present an efficient technology to simultaneously measure a molecule’s size and UV/Vis spectrum: UV/Vis Diffusion-Ordered Spectroscopy ( 👀 full article here!).
As a practical example, we show how it disentangles the UV spectrum of coffee. The two main components of coffee, caffeine and chlorogenic acid, have strongly overlapping UV spectra. However, their sizes are different, so in the UV/Vis-DOSY spectrum the component spectra are at different positions on the diffusion-coefficient axis, and cleanly separated. This makes quantifying the component concentrations easy, and so helps crafting the perfect cup of coffee by balancing acidity or enhancing aroma.

Why It Matters❓ Simultaneously characterizing the size and chemical structure of molecules or particles is crucial for many practical applications. For instance, the specific combination of nanoparticle size and composition directly impacts their properties, from reactivity to stability, influencing applications in drug delivery, catalysis, and beyond.

Here's why it's a game-changer:
1️⃣ Efficiency: No need for time-consuming separate measurements of size and absorption spectrum.
2️⃣ Cost-effective: You can transform any UV/Vis or infrared spectrometer into a size-sensitive instrument by using our optical-DOSY cell or chip (see 👇 )
3️⃣ Versatility: Optical DOSY works for a wide range of sample types: supramolecular complexes, nanoparticles, polymers, biomolecules,…

Looking forward to bring this technology into every lab around the world!